三氯卡班对小鼠血浆内源性物质影响的代谢组学研究

三氯卡班被认定为一种新型的环境污染物,可能对动植物和人体产生危害,为探究三氯卡班的有害作用机制,选择C57BL6小鼠作为载体,利用分子生物学和报告基因方法考察了三氯卡班对肝脏的作用,同时利用代谢组学技术考察三氯卡班对血浆内源性代谢物变化的影响。结果表明,三氯卡班是核受体CAR的激活剂,可以提高肝脏CYP2b10的m RNA表达。同时血浆主要的内源性代谢物也产生了显著性变化,血浆中的脂肪酸比例都呈下降趋势,肉毒碱与乙酰肉碱的比例都呈上升趋势,花生四烯酸与肌酸的比例都呈上升趋势,这都与核受体CAR被激活密切相关,由此说明利用代谢组学技术能够全面地反映三氯卡班所造成的对机体的影响。     

PVA降解混合菌系生长和产酶的营养条件分析

研究碳源、氮源以及不同金属离子对PVA降解混合菌系生长和产酶的影响。结果表明,混合菌系生长过程中无机氮源优于有机氮源;补充碳源可促进混合菌系的生长,但酶活比不添加时稍有降低。金属离子对酶活影响的正交实验表明Mg2＋浓度影响最大,其次是Fe2＋和K＋浓度,Ca2＋、Mn2＋、Zn2＋和Cu2＋浓度影响较小;最佳浓度分别为Mg2＋0.05 g/L、Fe2＋0.04 g/L、K＋2 g/L和Ca2＋0.05 g/L。     

国内外可持续发展评价方法对比分析

国际、国内很多组织都对可持续性评价方法进行过研究分析,但大多是特定的案例研究.目前国内外对可持续发展评价方法没有一个全面系统的分析比较,使得不同地区比较起来很困难.本文对各种评价方法如环境可持续性指数法、生态足迹法、能值分析法和指标综合评价法的来源、理论和应用作了介绍.得出各方法适用范围:可持续性指数法适合于国家间的综合评价;生态足迹和能值分析法适合于各种范围,包括国家、区域、地区和小系统;指标体系综合评价法对于小范围更合适.同时对各种方法的优势和缺陷进行了分析讨论,得出:可持续性指数法信息量大,但是计算复杂;生态足迹法计算过程简单,但是缺失一些可持续性信息;能值分析法考虑问题全面,但是其原理涉及热力学知识,很难被一些学者认同;指标体系评价法变通性较大,可随着评价系统的变化而进行调整,但是主观性较强.通过分析指出不同方法适用范围并指出每种分析方法的优势和不足,为以后选择合适的分析方法评价对象的可持续性提供依据.     

MicroRNA: a novel implication for damage and protection against ionizing radiation

Environmental Science and Pollution Research - Ionizing radiation (IR) is a form of high energy. It poses a serious threat to organisms, but radiotherapy is a key therapeutic strategy for various...     

Development of highly efficient and reusable magnetic nitrogen-doped carbon nanotubes for chlorophenol removal

Environmental Science and Pollution Research - Nitrogen-doped carbon nanotubes (N-CNTs) were synthesized via a hydrothermal method and further modified with magnetic Co0.5Cu0.5Fe2O4 nanoparticles...     

Desorption of CO2, SO2, and NH3 in the vacuum evaporation of desulfurization wastewater

Environmental Science and Pollution Research - Mechanical vapor compression and multi-effect evaporation have been widely used in achieving zero discharge of desulfurization wastewater as they are...     

Dietary exposure to di-isobutyl phthalate increases urinary 5-methyl-2′-deoxycytidine level and affects reproductive function in adult male mice

Phthalates are a large family of ubiquitous environmental pollutants suspected of being endocrine disruptors. Epidemiological studies have associated phthalate metabolites with decreased reproductive parameters and linked phthalate exposure with the level of urinary 5-methyl-2′-deoxycytidine(5mdC, a product of methylated DNA). In this study, adult male mice were exposed to 450 mg di-isobutyl phthalate(DiBP)/(kg·day) via dietary exposure for 28 days. Mono-isobutyl phthalate(Mi BP, the urinary metabolite) and reproductive function parameters were determined. The levels of 5mdC and 5-hydroxymethyl-2′-deoxycytidine(5hmdC) were measured in urine to evaluate if their contents were also altered by DiBP exposure in this animal model. Results showed that DiBP exposure led to a significant increase in the urinary 5mdC level and significant decreases in sperm concentration and motility in the epididymis, accompanied with reduced testosterone levels and downregulation of the P450 cholesterol side-chain cleavage enzyme(P450scc) gene in the mice testes. Our findings indicated that exposure to DiBP increased the urinary 5mdC levels,which supported our recent epidemiological study about the associations of urinary 5mdC with phthalate exposure in the male human population. In addition, DiBP exposure impaired male reproductive function, possibly by disturbing testosterone levels; P450scc might be a major steroidogenic enzyme targeted by DiBP or other phthalates.     

石化行业有机液体储罐VOCs损耗估算方法浅析

总结了实测法、公式法、模型法等国内外石化行业有机液体储罐VOCs排放估算方法的主要特点和适用范围;运用公式法估算国内某石化企业典型油品储罐的VOCs排放量;分析了在我国直接套用美国环保署(EPA)开发的TANKS模型存在的问题;根据估算方法的实际应用研究,就美国AP-42源强手册第五版第七章(chapter 7:Liquid storage tank)中评价公式的"本土化"提出相关的建议。     

大兴安岭地区生态产品优势分析研究

大兴安岭地区生态优良、环境优美、地域广阔、森林浩瀚,是特有的寒温带生态系统.近年来,省委省政府落实"绿水青山就是金山银山"发展理念,结合我省大小兴安岭地区生态优势,制定保护规划、实施天保工程,有效提高了森林生态系统的服务功能.大兴安岭地区何以能生产出优质的生态产品?以蓝莓产业和产品为案例进行分析,认为:大兴安岭地区整体生态优势明显,主要体现在具有"冬季寒冷自然休眠、夏季昼长温差大"的气候条件;具有"纬度高、山坡缓、河流繁、水量大"的地理特征;具有"气洁、水清、土沃、排放少"的环境优势;具有"林广、树密、生物多样、生境完整"的生态优势;具有"质优、安全、营养、环保"的产品品质.     

本溪地区灰霾天气时空分布特征分析研究

近年来,灰霾天气对本溪地区的影响越来越严重,由霾引发的环境污染对人们生产生活造成的影响也越来越大,因此对灰霾天气发生的时空分布特征的研究就尤为重要.文章运用本溪地面观测2012-2014年本溪市、本溪县、桓仁县3个国家基本站的观测资料,对霾日进行筛选和统计,分析本溪地区霾日发生的时空分布特征,本溪地区霾日数呈逐年增长趋势,2014年霾日数增长迅速.本溪地区冬半年霾日明显多于夏半年,两县霾日少于市区,空气质量优于市区.